Product Category:

Antifibrinolytic Agent

Composition:

TRANEXAMIC ACID TABLETS IP (250 MG)

Therapeutic Category:

Haemostatic Agent

Mechanism of Action:

Tranexamic acid is an antifibrinolytic agent that works by inhibiting the activation of plasminogen to plasmin. Plasmin is responsible for breaking down blood clots. By inhibiting this process, tranexamic acid helps to stabilize blood clots and prevent excessive bleeding.

Indications:

Indicated for short term treatment of haemorrhage (bleeding) or risk of haemorrhage in those with increased fibrinolysis or fibrinogenolysis caused due to Prostatectomy and bladder surgery, Menorrhagia, Epistaxis, Conisation of the cervix and Traumatic hyphaema. It is also used in the management of bleeding disorders such as dental extraction in haemophiliacs.

Dosage:

Prostatectomy: Prophylaxis and treatment of haemorrhage in high risk patients should commence per- or post-operatively with an injectable form; thereafter 4 tablets three to four times daily until macroscopic haematuria is no longer present.

Menorrhagia: Recommended dosage is 4 tablets 3 times daily as long as needed for up to 4 days. If very heavy menstrual bleeding, dosage may be increased. A total dose of 4g daily (16 tablets) should not be exceeded. Treatment with tranexamic acid should not be initiated until menstrual bleeding has started.

Epistaxis (Nosebleed): When repeated bleeding is anticipated, oral therapy (4 tablets three times daily) should be administered for 7 days.

Cervix Conisation: 6 tablets three times daily

Traumatic Hyphaema (Blood in the anterior chamber of eye): 4-6 tablets 3 times daily. The dose is based on 25mg/kg three times a day.

Haemophilia: In the management of dental extractions, 4-6 tablets every eight hours. The dose is based on 25mg/kg.

Pack Size:

Available in 10 x 10’s Blister pack.