Product Category:

Analgesics and Antipyretics

Composition:

Ibuprofen and Paracetamol Tablets IP (400mg and 325mg)

Therapeutic Category:

NSAIDs+ Centrally acting analgesic

Mechanism of Action:

Ibuprofen is a non-selective inhibitor of cyclooxygenase (an enzyme involved in prostaglandin and thromboxane synthesis via the arachidonic acid pathway). The inhibition of the enzyme (COX-2) is known to decrease the synthesis of prostaglandins involved in mediating inflammation, pain, and fever. The exact mechanism of action of paracetamol has not been fully understood. Studies show that it has the ability to inhibit the cyclooxygenase (COX) pathways & is also thought to exert central actions which ultimately lead to the alleviation of pain symptoms. It has been shown that the antipyretic property of paracetamol is probably because of the action on heat-regulating centers in the brain, resulting in peripheral vasodilation, sweating, and loss of body heat.

Indications:

The combination of ibuprofen and paracetamol is used in the symptomatic management of moderate fever, pain, and inflammation, including: migraine headache, primary dysmenorrhea.

Dosage:

One Tablet 3-4 times daily or as directed by the physician

Pack Size:

10*10s (Blisters)