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LIDOCAINE AND PRILOCAINE CREAM USP (2.5% W/W/ 2.5% W/W)
Product Category: Anaesthetic
Composition: LIDOCAINE AND PRILOCAINE CREAM USP (2.5% W/W/ 2.5% W/W)
Therapeutic Category: Local Anaesthetic
Mechanism of Action: Lidocaine and Prilocaine are amide-type local anaesthetic agents which stabilize neuronal membranes by inhibiting the ionic fluxes required for the initiation and conduction of impulses, thereby effecting local anesthetic action.
Indications:
Liprox Cream is indicated for:
✔️ Topical anaesthesia of the skin, in adults and in the paediatric population, in connection with:
✔️ needle insertion, e.g. intravenous catheters or blood sampling;
✔️ superficial surgical procedures;
✔️ Topical anaesthesia of the genital mucosa, e.g. prior to superficial surgical procedures or infiltration anaesthesia; in adults and adolescents ≥ 12 years
✔️ Topical anaesthesia of leg ulcers to facilitate mechanical cleansing/debridement in adults only.
Dosage:
Adults and adolescents 12 years of age and above
| Indication/Procedure | Dosage and Application Time |
| Skin | |
| Minor procedures, e.g. needle insertion and surgical treatment of localised lesions. | 2 or approx. 1.5 g/10 cm 2 for 1 to 5 hours |
| Dermal procedures on newly shaven skin of large body areas, e.g. laser hair removal (self-application by patient) | Maximum recommended dose: 60 g. Maximum recommended treated area; 600 cm 2 for a minimum of 1 hour, maximum 5 hours |
| Dermal surgical procedures on larger areas in a hospital setting, e.g. split-skin grafting. | Approx 1.5-2 g/10 cm 2 for 2 to 5 hours |
| Skin of male genital organs Prior to injection of local anaesthetics Skin of female genital organs Prior to injection of local anaesthetics | 1 g/10 cm 2 for 15 minutes 1-2 g/10 cm 2 for 60 minutes |
| Genital mucosa | |
| Surgical treatment of localised lesions, e.g. removal of genital warts and prior to injection of local anaesthetics | Approx 5-10 g of cream for 5-10 minutes |
| Prior to cervical curettage | 10 g of cream should be administered in the lateral vaginal fornices for 10 minutes |
| Leg ulcer(s) | |
| Adults only Mechanical cleansing/debridement | Approx 1-2 g/10 cm 2 up to a total of 10 g to the leg ulcer(s) Application time: 30-60 minutes. |
Paediatric patients 0-11 years of age
| Age group | Procedure | Dosage and Application time |
| Minor procedures, e.g. needle insertion and surgical treatment of localised lesions | Approx 1g/10 cm 2 for one hour | |
| Newborn infants and infants 0-2 months | Up to 1 g and 10 cm 2 for one hour | |
| Infants 3-11 months | Up to 2 g and 20 cm 2 for one hour | |
| Toddlers and children 1-5 years | Up to 10 g and 100 cm 2 for 1-5 hours | |
| Children 6-11 years | Up to 20 g and 200 cm 2 for 1-5 hours | |
| Paediatric patients with atopic dermatitis | Prior to removal of mollusca | Application time: 30 minutes |
Pack Size: Available in 15 gm laminated tube.
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