Hiopen 20

Product Category: Drugs for GI Disorders

Composition: Hyoscine Butylbromide Tablets IP (20mg)

Therapeutic Category: Antimuscarinic, Anticholinergic (Anti-spasmodic)

Mechanism of Action: Hyoscine butylbromide(HBB) is an anticholinergic agent that exerts a spasmolytic action on the smooth muscle of the gastro-intestinal, biliary and genito-urinary tracts. It is a quaternary ammonium compound which blocks the action of acetylcholine at parasympathetic sites (both muscarinic and nicotinic receptors) in smooth muscles and secretory glands. HBB reduces the motility of the gastrointestinal tract and the urogenital tracts, demonstrating its usefulness in the relief of spasms in these regions, which may be associated with gastroenteritis, colitis, inflammatory bowel disease, diverticulitis, biliary colic, cystitis, ureteric colic, and primary dysmenorrhea. (Samuels, 2009) Samuels, L. A. (2009). Pharmacotherapy Update: Hyoscine Butylbromide in the Treatment of Abdominal Spasms. Clinical Medicine. Therapeutics, 1, CMT.S1134. https://doi.org/10.4137/cmt.s1134

Indications: Hyoscine Butylbromide is indicated for the relief of genito-urinary and gastro- intestinal spasms as well as for the symptomatic relief of Irritable Bowel Syndrome.

Dosage: Adults: Two 10mg tablets or one 20mg four times daily (20mg QID) For the symptomatic relief of Irritable Bowel Syndrome, the recommended starting dose is 10mg tablet three times daily, this can be increased up to two 10mg or one 20mg tablet four times daily if necessary.(Initially 10mg TID, can be increased to 20mg QID)

Pack Size: 20x10s (Blisters)